There is a book about sweating the small stuff... but I think it's important not to overlook small stuff too.
I often think of how we measure "quality of life". Is it the number of things we have? Is it the number of friends we have on social media sites or in real life? Is it measured in how long we have been with a significant other? Can we say we have quality of life living alone; doing what we want, whenever we want? Is it achieving a certain status in life?